Dr. Regine is a leader in the field of radiation oncology and a recognized expert in the areas of GI and CNS malignancies. He has served as a principal investigator for multiple NCI-sponsored clinical trials and his research has defined new standards of care for patients. As Executive Director of the Maryland Proton Treatment Center, he leads the first and most advanced facility of its kind in the Baltimore-Washington, DC region – providing nearly 4,000 cancer patients to date with precise, "pencil-beam" technology to treat solid tumors.
Dr. Regine is co-inventor of the “GammaPod,” the first treatment system dedicated to the stereotactic radiation of early-stage breast cancer and is co-editor of “Principles and Practices of Stereotactic Radiosurgery,” the first comprehensive textbook of its kind. He has been a member of the GI and Brain Tumor steering committees for the NCI sponsored national cooperative clinical trials group known as NRG Oncology and has been the chairman of the GI section of the National Oral Board examination for trainees in radiation oncology.